Lytle Pharmacy

Lytle Pharmacy is Rochester’s Oldest Drug Store

No living person in the Rochester area remembers when there wasn’t a pharmacy located in the Opera House block at the corner of Fourth & Main streets. Ever since the building first opened its doors in 1890, a pharmacy sign has been hanging in its front window. Robert A. Lytle is the current – and longest tenured – proprietor of the drug store business that was operated by John T. Norton when the Opera House block welcomed its first tenants 126 years ago.

Hours:
Monday through Friday 
9 a.m. to 6 p.m.

Saturday
10 a.m. to 4 p.m.

340 S Main St, Rochester, MI 48307
(248) 651-8511

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